Abstract: To optimize the weight of torpedo launch tube and perform optimization design of large depth torpedo launch tube, a mathematical model is built with analytical method, and genetic algorithm is adopted to acquire the global opti-mal solution of the nonlinear discrete optimization problem for the minimum weight design of torpedo launch tube meeting strength and stability requirements on MATLAB platform. Results indicate that on the premise of meeting the existing tactical and technical indexes, there is still a large space for the weight optimization design of existing launch tube, but the existing launch cannot meet the requirement of large depth launch in the future. This study programs the design of torpedo launch tube for the purposes of engineering application and benefiting optimization design.